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Computer Talk - Business Computer - Computer Games - Computer Software Computer Shop - Computer Mice - New Computer - Antivirus Software Listen to Coronavirus Patient Zero Multithreaded Computer Architecture RRP $157.95 ![]() Multithreaded computer architecture has emerged as one of the most promising and exciting avenues for the exploitation of parallelism. This new field represents the confluence of several independent research directions which have united over a common set of issues and techniques. Multithreading draws on recent advances in dataflow, RISC, compiling for fine-grained parallel execution, and dynamic resource management. It offers the hope of dramatic performance increases through parallel execution for a broad spectrum of significant applications based on extensions to `traditional' approaches. RRP $275.99 ![]() Bring your computer literacy course back to the BASICS. COMPUTER LITERACY BASICS: A COMPREHENSIVE GUIDE TO IC3 provides an introduction to computer concepts and skills, which maps to the newest Computing Core Certification (IC3) standards. Designed with new learners in mind, this text covers Computing Fundamentals, Key Applications, and Living Online - everything students need to pass the IC3 exam, and finish the course as confident computer users. RRP $256.99 ![]() This definitive new volume brings together scientists from government, industry, and the academic worlds to explore ways in which to capitalize on resources for new ventures into the next generation of supercomputers. The wealth of information on state-of-the-art scientific developments contained in this single volume makes Supercomputers an invaluable resource for management scholars and government policymakers interested in high technology companies and strategic planning. RRP $354.99 ![]() For the past 100 years the mainstay of therapy for rheumatoid arthritis (RA) has been aspirin or other drugs of the non-steroid anti-inflammatory group. In 1971 Vane pro posed that both the beneficial and toxic actions of these drugs was through inhibition of prostaglandin synthesis. The recent discovery that prostaglandins responsible for pain and other symptoms at inflammatory foci are synthesized by an inducible cyclooxygenase (COX-2) that is encoded by a gene distinct from that of the consti tutive enzyme (COX-I) provided a new target for therapy of RA. A drug that would selectively inhibit COX-2 would hopefully produce the symptomatic benefit provided by existing NSAIDs without the gastrointestinal and renal toxicity due to the inhibition of COX-I. Drugs selective for COX-2 are now available. Experimental studies have shown them to be effective with minimal toxicity, and in clinical trials gastric and renal toxicities are less. Highly selective COX-2 inhibitors, perhaps designed with knowledge of the crystal structures of COX-I and COX-2, are also available. Other experimental studies, including those in animals lacking effective genes for COX-lor COX-2 and in experimental carcinomas, suggest there is still much to be learned of the pathophysiological functions of these enzymes. The inflammatory response is a complex reaction involving many mediators that derive from white blood cells, endothelial cells and other tissues. Preliminary data have revealed that inhibitors of the cytokines and adhesion molecules that play a crucial role in the migration of white cells to inflammatory sites may be useful in RA. Computer Systems Analyst Career (special Edition) RRP $18.99 ![]() In clear, easy-to-grasp language, the author covers many of the topics that you will need to know in order to win your dream job and be the first in line for a promotion. Search
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